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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPAPDC1A All Species: 29.39
Human Site: T129 Identified Species: 46.19
UniProt: Q5VZY2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VZY2 NP_001025230.1 271 30395 T129 M N S E M H C T G D P D L V S
Chimpanzee Pan troglodytes XP_001170623 223 25141 F82 P D F F Y R C F P D G L A H S
Rhesus Macaque Macaca mulatta XP_001092746 343 37863 I188 F T N T I K L I V G R P R P D
Dog Lupus familis XP_535038 333 36609 T191 M N S E M H C T G D P D L V S
Cat Felis silvestris
Mouse Mus musculus Q0VBU9 271 30425 T129 M N S E M R C T G D P D L V S
Rat Rattus norvegicus O08564 282 31978 R127 K Y S I G R L R P H F L A V C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514919 461 51675 T135 M N S E M H C T G D P D L V S
Chicken Gallus gallus XP_426544 322 36285 T180 M N S E M H C T G D P D L V S
Frog Xenopus laevis Q6GQ62 226 25153 G85 L F R C F P D G Q E S P G L H
Zebra Danio Brachydanio rerio XP_002664129 282 31516 T136 M N A K M L C T G E P D L V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623887 268 30640 D126 F F W R C F P D G Q T N P D F
Nematode Worm Caenorhab. elegans Q10022 341 39009 T180 Y I T D Y T C T G P P E L V L
Sea Urchin Strong. purpuratus XP_787511 258 29394 T116 M T T D L K C T G D L D T I N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9XI60 290 32684 L148 H N V T K N V L C T G A K D V
Baker's Yeast Sacchar. cerevisiae Q05521 289 33495 T145 L P L D T L F T A K D V C T T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.2 48 77.7 N.A. 99.2 25.5 N.A. 48.1 77.3 52.4 71.2 N.A. N.A. 47.9 24.3 46.1
Protein Similarity: 100 64.9 60 79.8 N.A. 99.2 41.1 N.A. 53.3 80.4 63.4 83.6 N.A. N.A. 66.7 39.8 64.2
P-Site Identity: 100 20 0 100 N.A. 93.3 13.3 N.A. 100 100 0 73.3 N.A. N.A. 6.6 40 40
P-Site Similarity: 100 26.6 13.3 100 N.A. 93.3 13.3 N.A. 100 100 20 93.3 N.A. N.A. 13.3 60 73.3
Percent
Protein Identity: N.A. N.A. N.A. 36.5 31.1 N.A.
Protein Similarity: N.A. N.A. N.A. 54.4 50.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 0 0 7 0 0 7 14 0 0 % A
% Cys: 0 0 0 7 7 0 60 0 7 0 0 0 7 0 7 % C
% Asp: 0 7 0 20 0 0 7 7 0 47 7 47 0 14 7 % D
% Glu: 0 0 0 34 0 0 0 0 0 14 0 7 0 0 0 % E
% Phe: 14 14 7 7 7 7 7 7 0 0 7 0 0 0 7 % F
% Gly: 0 0 0 0 7 0 0 7 60 7 14 0 7 0 0 % G
% His: 7 0 0 0 0 27 0 0 0 7 0 0 0 7 7 % H
% Ile: 0 7 0 7 7 0 0 7 0 0 0 0 0 7 0 % I
% Lys: 7 0 0 7 7 14 0 0 0 7 0 0 7 0 0 % K
% Leu: 14 0 7 0 7 14 14 7 0 0 7 14 47 7 7 % L
% Met: 47 0 0 0 40 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 47 7 0 0 7 0 0 0 0 0 7 0 0 7 % N
% Pro: 7 7 0 0 0 7 7 0 14 7 47 14 7 7 0 % P
% Gln: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % Q
% Arg: 0 0 7 7 0 20 0 7 0 0 7 0 7 0 0 % R
% Ser: 0 0 40 0 0 0 0 0 0 0 7 0 0 0 47 % S
% Thr: 0 14 14 14 7 7 0 60 0 7 7 0 7 7 7 % T
% Val: 0 0 7 0 0 0 7 0 7 0 0 7 0 54 7 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 7 0 0 14 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _